Saturday, June 23, 2012

New Eye Drop: Refresh Optive Advanced


There is a new refresh eye drop available called Refresh Optive Advanced. My favorite eye drop, Refresh Endura, stopped being produced in the US in 2010 and I was in quite a pickle looking for an alternative. With other drops, nothing seemed to soothe my eyes as much as Refresh Endura which has active ingredients of Polysorbate 80 and Glycerin (1%).  I eventually found  that I was still able to order preservative-free Refresh Endrua from Canadian website www.well.ca (similar to sites such as www.drugstore.com in the US).  I order these in bulk every couple of months. 

It turns out that Allergan replaced Refresh Endura with Refresh Optive, which a wonderful blogger Sjoggie Stahmer recently wrote about in more detail. Refresh Optive's active ingredients are 0.5% carboxymethylcellulose and 0.9% glycerin. I did try these drops and did not find them to be as effective in alleviateing my dry eyes. So I was pleased to see a new Refresh drop at the drugstore called Refresh Optive Advanced.  It's active indgredients are really a combination of those found in Refresh Endrua and Refresh Optive: Glycerin (1%), Polysorbate 80 (0.5%), and Carboxymethylcellulose Sodium (0.5%).  Allergan advertises the drops as working on all three layers of the tears--the outer  lipid layer, the middle water or aqueous layer, and the bottom mucouid or mucuous layer.

The drops come in a bottle, not individual vials, which is an indication that they do contain preservatives.  I called Allergan and spoke with a medical representative to find out if Refresh Optive Advanced comes in a preservative free version or if there are plans to bring it to market soon.  As of now, these drops all contain preservatives and the representative was not aware if a preservative free version would become available. She recommended waitng 15 to 30 minutes before switching between different types of eye drops.  In my case that would be between the Refresh Optive Advanced and the Refresh Endura.

I do like the feel of the Refresh Optive Advanced, but when I did try to switch between them and Refresh Endura,  my eyes began to burn and sting.  I am not sure if this is a result of the preservatives in the Optive Advanced, but in my case it seems that I have to stick to one drop or the other to prevent that reaction.  Drops with preservatives can cause irritation, redness, and additional dryness for some patients.  I am hoping that Allergan will bring a preservative free version of the Optive Advanced to market.




*I have no relationship with any of the companies whose products are mentioned in this post*





10 comments:

  1. I am glad that my post was helpful! :o)

    ReplyDelete
  2. Thanks so much for your post. I've been paying a fortune for Restasis and I'm glad to know about the Canadian source for the preservative-free vials of Refresh Endura. I just ordered some--hope it will work. If not, I'll try the Refresh Optive Advanced, but I tend to be very sensitive to preservatives. Allergan should be ashamed of what they charge for Restasis (which has ingredients similar to Endura, is preservative free, and has the addition of the active ingredient cyclosporine which has never "cured" my dry eyes like it's supposed to. Also, when you read the fine print of the package insert, it looks like cyclosporine may have some carcinogenic effects. At least it does when they feed it to mice, so who knows. I think that the base ingredients are the reason Restasis helps--and Allergan figured out that removing the relatively bargain over-the-counter Endura from the American market would help drive their huge profits on prescription Restasis. (For a 90-day supply, they charge my insurance $770 (!) and my insurance bills me $192 (!!). Good grief--these are eye drops. Again, appreciated your post!

    ReplyDelete
  3. Bad news for those of us whose eyes survive on Refresh Endura imported from Canada. Went to place my regular 24 box order the other day and found that Well.ca will no longer ship these eyedrops to the USA. I normally don't beleive in conspiracy theories, but I'm beginning to think Allergan is deliberately sabotaging me as a way of improving sales of Restasis...

    ReplyDelete
  4. This stuff is down t earth, hats off buds out there. eye drops

    ReplyDelete
  5. I order these in bulk every couple of months. Can-C

    ReplyDelete
  6. Good news! I just learnt that they have the preservative free Optive advanced drops. You can find them at Walgreen.com

    ReplyDelete
  7. I listen about it and ordered to. It is very good for eyes.
    Cyclomune 0.05

    ReplyDelete
  8. Very good and informative blog. thanks for sharing it.
    Megabrom Eye Drop

    ReplyDelete
  9. I read your blog. It is Very good and Jannat suggest you to take this drop for your eyes.
    Jannat Online Shopping

    ReplyDelete
  10. The utility model has the advantages of simple structure and stable and reliable performance, and is an ideal device for wetting tobacco thin slice with carboxymethyl cellulose sodium at present.

    ReplyDelete